Bioavailability of Phloretin and Phloridzin in Rats
نویسندگان
چکیده
منابع مشابه
Purification and characterization of a novel phloretin-2′-O-glycosyltransferase favoring phloridzin biosynthesis
Phloretin-2'-O-glycosyltransferase (P2'GT) catalyzes the last glycosylation step in the biosynthesis of phloridzin that contributes to the flavor, color and health benefits of apples and processed apple products. In this work, a novel P2'GT of Malus x domestica (MdP2'GT) with a specific activity of 46.82 μkat/Kg protein toward phloretin and uridine diphosphate glucose (UDPG) at an optimal tempe...
متن کاملMetabolism of phloridzin by Erwinia herbicola: nature of the degradation products, and the purification and properties of phloretin hydrolase.
Erwinia herbicola Y46 degrades phloridzin to yield phloretin, phloroglucinol, and phloretic acid, when grown on defined medium containing phloridzin as the sole source of carbon. The identities of the intermediates isolated from culture filtrates were established by co-chromatography and by ultraviolet absorption spectra. Only 3 of 11 strains of this species, and none of the 12 species of bacte...
متن کاملEffects of phloretin and phloridzin on Ca2+ handling, the action potential, and ion currents in rat ventricular myocytes.
The effects of the phytoestrogens phloretin and phloridzin on Ca(2+) handling, cell shortening, the action potential, and Ca(2+) and K(+) currents in freshly isolated cardiac myocytes from rat ventricle were examined. Phloretin increased the amplitude and area and decreased the rate of decline of electrically evoked Ca(2+) transients in the myocytes. These effects were accompanied by an increas...
متن کاملEffects of Phloretin and Phloridzin on Ca Handling, the Action Potential, and Ion Currents in Rat Ventricular Myocytes
The effects of the phytoestrogens phloretin and phloridzin on Ca handling, cell shortening, the action potential, and Ca and K currents in freshly isolated cardiac myocytes from rat ventricle were examined. Phloretin increased the amplitude and area and decreased the rate of decline of electrically evoked Ca transients in the myocytes. These effects were accompanied by an increase in the Ca loa...
متن کاملInhibition of oxidation of aqueous emulsions of omega-3 fatty acids and fish oil by phloretin and phloridzin.
The antioxidant properties of two apple dihydrochalcones, namely phloretin and phloridzin, were evaluated and compared with those of alpha-tocopherol and butylated hydroxytoluene (BHT). The effects were studied in an oil-in-water emulsion system containing methyl linolenate (ML), methyl eicosapentaenoate (MEPA), and methyl docosahexaenoate (MDHA) in which oxidation was initiated by the peroxyl ...
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ژورنال
عنوان ژورنال: The Journal of Nutrition
سال: 2001
ISSN: 0022-3166,1541-6100
DOI: 10.1093/jn/131.12.3227